Liquid Presentation

Each 5 ml Contains:
Disodium Hydrogen Citrate 1.53 g / 1.40 g

This medication is used to make the urine less acidic. Urine that is less acidic helps the kidneys get rid of uric acid, helping to prevent gout and certain types of kidney stones (urate). This medication can also prevent and treat certain metabolic problems (acidosis) caused by kidney disease. Citric acid and citrate salts (which contain potassium and sodium) belong to a class of drugs known as urinary alkalinizers.

Uses

• Kidney stones
• Urine alkalinization
• Urinary Tract Infection
• Micturition

Mechanism of action

Disodium hydrogen citrate is metabolized to bicarbonates, which increase urinary pH by increasing the excretion of free bicarbonate ions, without producing systemic alkalosis when administered in recommended doses. A rise in urinary pH increases the solubility of cystine in the urine and the ionization of uric acid to more soluble urate ion. By maintaining an alkaline urine, the actual dissolution of uric acid stones may be accomplished.

Side Effects

The product is possible safe for most adults. There is no disadvantage associated with the product if taken under the recommended usage however Diarrhoea, Nausea, Vomiting, Tiredness, Frequent urge to urinate, stomach cramps and Flatulence can occur in some patients.

Interactions

Disodium hydrogen citrate reduces the gastric acidity which can decrease the absorption of the following drugs:

• Aspirin and other salicylates
• Lithium
• Quinidine
• Ritonavir
• Ciprofloxacin
• Moxifloxacin
• Doxycycline
• Tetracycline
• Ketoconazole
• Itraconazole